Hairy Cell Leukemia
Harwood Academic Publishers,The Netherlands (Verlag)
978-90-5823-009-6 (ISBN)
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Hairy cell leukemia has been the subject of much debate during the past forty years. The etiology and pathogenesis of the disease is still unclear, and the origin of the unusual "hairy" B-lymphocyte is still to be clarified with certainty. Nevertheless, clinical advances in the therapy of this disease have resulted in the control and virtual cure of the majority of cases with the disorder.
This volume addresses all aspects of hairy cell leukemia, embracing the history of the disease, morphology, electron-microscopy, histopathology, biological and immunological aspects, possible etiological environmental links, diagnosis and differential diagnosis and all aspects of modern therapy.
The authors are established specialists in this field and many have been leaders in the investigation and therapy of hairy cell leukemia, contributing years of their clinical and scientific experience in the search for solutions. Collectively their contributions bring together a wealth of up-to-date information to present a comprehensive and invaluable guide to the disease and current treatment therapies.
1. Hairy Cell Leukemia: An Historical Perspective 2. Biology of the Hairy Cell 3. Pathology of Hairy Cell Leukemia 4. Ultrastructural Features of Hairy Cell Leukemia: Transmission and Scanning Electron Microscopy 5. Cytogenetics, Molecular Genetics and Immunophenotyping in Hairy Cell Leukemia 6. Epidemiology Hairy Cell Leukemia 7. Clinical Manifestations and Differential Diagnosis of Hairy Cell Leukemia 8. Unusual Manifestations of Hairy Cell Leukemia 9. Cytokines and Cytokine Receptors in Hairy Cell Leukemia: Clinical Relevance and Correlation with Disease Activity 10. The Role of Splenectomy in Hairy Cell Leukemia 11. Past and Present Role of Interferon in Hairy Cell Leukemia 12. Past and Present Role of Pentostatin in Hairy Cell Leukemia 13. Mechanisms of Action, Pharmacokinetics and Routes of Administration of 2-Chlorodeoxyadenosine in Hairy Cell Leukemia 14. Treatment of Hairy Cell Leukemia with 2-Chlorodeoxyadenosine 15. Future Directions Toward the Cure of Patients with Hairy Cell Leukemia
| Erscheint lt. Verlag | 9.3.2000 |
|---|---|
| Sprache | englisch |
| Gewicht | 635 g |
| Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Hämatologie |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
| Studium ► 2. Studienabschnitt (Klinik) ► Pathologie | |
| ISBN-10 | 90-5823-009-0 / 9058230090 |
| ISBN-13 | 978-90-5823-009-6 / 9789058230096 |
| Zustand | Neuware |
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