Essential Aspects of Atopic Dermatitis

Georg Rajka (Autor)

Buch | Softcover

XVI, 261 Seiten

2011 | 1. Softcover reprint of the original 1st ed. 1989
Springer Berlin (Verlag)
978-3-642-74768-7 (ISBN)

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"Le secret d'ennuyer est celui de tout dire. " Voltaire (Discours sur l'homme) Atopic dermatitis (AD) is frequently seen by dermatologists and pediatricians, by allergologists, and by many practitioners. The amount of data on AD is vast as it has been recognized for a very long time, has a worldwide distribution, and has a chapter or section devoted to it in every textbook or review of skin diseases. Difficulty arises in evaluating certain aspects of this complex disease, for many studies have been concerned with only some of its facets and with small numbers of patients. In addition a monograph on AD should also try to encompass the important theoretical aspects of this fascinating disease. There fore, the problem in presenting a monograph on AD lies more in the critical se lection than in the gathering of information, much of which is conflicting. This applies both to basic data and to details. Furthermore, the many divergent opinions in almost every field make it extremely difficult to draw unanimous conclusions. Consequently, the author has no option but to quote antagonistic views, try to make a compromise between these, and express his own opinion based on clinical experience and fundamental literary work.

1 History and Nomenclature.- 1.1 History.- 1.2 Nomenclature.- References.- 2 Clinical Aspects.- 2.1 Prevalence.- 2.2 Course.- 2.3 Prognosis.- 2.4 Basic Clinical Features.- 2.5 Morphology and Distribution.- 2.6 Other Essential Features.- 2.7 Special Clinical Types.- 2.8 Correlations Between Distribution and Pathomechanism.- 2.9 Complications Caused by Living Agents.- 2.10 Complication of the Malfunctioning Immunomechanisms.- 2.11 Other Complications.- 2.12 Associated Conditions; Proven Correlations.- 2.13 Xerosis-Ichthyosis Group.- 2.14 Probable Correlations.- 2.15 Possible Correlations.- 2.16 Coexistence of AD with Common Skin Diseases.- References.- 3 Itch.- 3.1 Short Survey.- 3.2 Role of Itch in AD.- References.- 4 Histopathological and Laboratory Findings.- 4.1 Histopathological Findings.- 4.2 Laboratory Findings.- References.- 5 Pathomechanism: Genetic and Immunological Factors.- 5.1 Genetic Factors.- 5.2 Atopic Allergens.- 5.3 Foods.- 5.4 Other Allergens from Living Agents.- 5.5 The Atopic Antibody.- 5.6 Contact Reactivity.- 5.7 Delayed (Tuberculin-Type) Reactivity.- 5.8 Other Reaction Types.- 5.9 Concluding Remarks.- References.- 6 Pathomechanism: Cells and Mediators.- 6.1 Mast Cells and Histamine.- 6.2 Eosinophils and Their Products.- 6.3 Cyclic Nucleotides.- 6.4 Eicosanoids.- 6.5 Complement.- 6.6 Other Mediators.- References.- 7 Pathomechanism: The Altered Skin.- 7.1 Itch.- 7.2 Alteration of Skin Structure and Some Consequences.- 7.3 Water Exchange.- 7.4 Paradoxical Vascular Responses.- 7.5 Other Alterations.- 7.6 Concluding Remarks.- References.- 8 Pathomechanism: Attempt at Synthesis.- 8.1 Animal Models.- 8.2 Attempt at Synthesis.- References.- 9 Factors Influencing the Course of AD.- 9.1 Seasonal Dependence.- 9.2 Climatic Factors.- 9.3 Some Environmental Factors.- 9.4 Socioeconomic Environment.- 9.5 Occupation.- 9.6 Psychological Factors.- 9.7 Other Factors.- References.- 10 Diagnosis and Grading (Severity).- 10.1 Diagnostic Criteria.- 10.2 Differential Diagnosis.- 10.3 Grading (Severity).- References.- 11 Prophylaxis.- 11.1 Food Avoidance.- 11.2 Inhalant Allergens.- 11.3 Occupational Prophylaxis.- 11.4 Other Measures.- References.- 12 Management of AD.- 12.1 Specific and Immunological Therapy.- 12.2 General Measures.- 12.3 Systemic Therapy.- 12.4 Topical Therapy.- 12.5 Concluding Remarks.- References.

Erscheint lt. Verlag	13.12.2011
Zusatzinfo	XVI, 261 p.
Verlagsort	Berlin
Sprache	englisch
Maße	155 x 235 mm
Gewicht	428 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Dermatologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pädiatrie
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
Schlagworte	allergy • Antibody • Antigen • Asthma • Atopische Dermatitis • Bacteria • bronchial asthma • Childhood • children • Diseases • immunity • Infection • Pain • pathogenesis • resistance
ISBN-10	3-642-74768-X / 364274768X
ISBN-13	978-3-642-74768-7 / 9783642747687
Zustand	Neuware