Cancer Immunotherapy

Paradigms, Practice and Promise

Buch | Hardcover

486 Seiten

2012 | 2013 ed.
Springer-Verlag New York Inc.
978-1-4614-4731-3 (ISBN)

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This work will provide a historical perspective on tumor immunotherapy, discuss fundamental mechanisms of failed tumor rejection, look at passive strategies to boost anti-tumor immunity, as well as have an in-depth look at active strategies to boost anti-tumor immunity.

Introduction.- Historical Perspectives and Current Trends in Cancer Immunotherapy.- T cell and Antigen-Presenting Cell Subsets in the Tumor Microenvironment.- Adoptive T Cell Transfer.- Dendritic Cell-Based Cancer Immunotherapy: Achievements and novel concepts.- Peptide and Protein-based Cancer Vaccines.- Antigen Targeting to Dendritic Cells for Cancer Immunotherapy.- Cytokines in the Treatment of Cancer.- Immune Co-signaling to Treat Cance.- Managing Regulatory T cells.- Myeloid-Derived Suppressor Cells in Cancer: Mechanisms and therapeutic perspectives .- Antibodies as Cancer Immunotherapy.- Targeted Toxins in Cancer Immunotherapy.- Miscellaneous Approaches and Considerations: TLR agonists and other inflammatory agents, anti-chemokine agents, infectious agents, tumor stroma targeting, age and sex effects, and miscellaneous small molecules.- Issues in Pre-clinical Models, Clinical Trial Design and Analytical Considerations in Developing and Evaluating Novel Cancer Immunotherapies.- Monitoring Antigen-Specific Responses in Clinical Trials of Immunotherapy.- Index

Erscheint lt. Verlag	7.11.2012
Zusatzinfo	X, 486 p.
Verlagsort	New York, NY
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Studium
ISBN-10	1-4614-4731-3 / 1461447313
ISBN-13	978-1-4614-4731-3 / 9781461447313
Zustand	Neuware