Joint Models for Longitudinal and Time-to-Event Data

With Applications in R

Dimitris Rizopoulos (Autor)

Buch | Hardcover

278 Seiten

2012
Crc Press Inc (Verlag)
978-1-4398-7286-4 (ISBN)

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In longitudinal studies it is often of interest to investigate how a marker that is repeatedly measured in time is associated with a time to an event of interest, e.g., prostate cancer studies where longitudinal PSA level measurements are collected in conjunction with the time-to-recurrence. Joint Models for Longitudinal and Time-to-Event Data: With Applications in R provides a full treatment of random effects joint models for longitudinal and time-to-event outcomes that can be utilized to analyze such data. The content is primarily explanatory, focusing on applications of joint modeling, but sufficient mathematical details are provided to facilitate understanding of the key features of these models.

All illustrations put forward can be implemented in the R programming language via the freely available package JM written by the author. All the R code used in the book is available at:
http://jmr.r-forge.r-project.org/

Dimitris Rizopoulos is an Assistant Professor at the Department of Biostatistics of the Erasmus University Medical Center in the Netherlands. Dr. Rizopoulos received his M.Sc. in Statistics in 2003 from the Athens University of Economics and Business, and a Ph.D. in Biostatistics in 2008 from the Katholieke Universiteit Leuven. Dr. Rizopoulos wrote his dissertation, as well as a number of methodological articles on various aspects of joint models for longitudinal and time-to-event data. He currently serves as an Associate Editor for Biometrics and Biostatistics, and has been a guest editor for a special issue in joint modeling techniques in Statistical Methods in Medical Research.

Introduction. Analysis of Longitudinal Data. Analysis of Time-to-Event Data. Joint Models for Longitudinal and Time-to-Event Data. Extensions of the Standard Joint Model. Diagnostics. Survival Probabilities and Prospective Accuracy Measures.

Erscheint lt. Verlag	9.7.2012
Reihe/Serie	Chapman & Hall/CRC Biostatistics Series
Zusatzinfo	6 Tables, black and white; 36 Illustrations, black and white
Verlagsort	Bosa Roca
Sprache	englisch
Maße	156 x 234 mm
Gewicht	536 g
Themenwelt	Studium ► Querschnittsbereiche ► Epidemiologie / Med. Biometrie
Themenwelt	Naturwissenschaften ► Biologie
ISBN-10	1-4398-7286-4 / 1439872864
ISBN-13	978-1-4398-7286-4 / 9781439872864
Zustand	Neuware