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Myocardial Ischemia (eBook)

From Mechanisms to Therapeutic Potentials
eBook Download: PDF
2006 | 2006
VIII, 204 Seiten
Springer US (Verlag)
978-0-387-28658-7 (ISBN)

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Effective new treatments of heart disease are based on a refined understanding of cellular function and the heart's response to environmental stresses. Not surprisingly therefore, the field of experimental cardiology has experienced a phase of rapid expo­ nential growth during the last decade. The acquisition of new knowledge has been so fast that textbooks of cardiology or textbooks of cardiovascular physiology are often hard-pressed to keep up with the most important conceptual advances. Witness the explosive increase in knowledge about signaling pathways of cardiac growth, transcrip­ tional regulation of cardiac metabolism, hormonal signaling, and the complex responses of the heart to ischemia, reperfusion, or ischemic preconditioning. This book is meant to bridge the gap between original literature and textbook reviews. It brings together inves­ tigators of various backgrounds who share their expertise in the biology of myocardial ischemia. Each chapter is a self-contained mini-review, but it will soon become apparent to the reader that there is also a common thread: Molecular and cellular cardiology has never been more exciting than now, but ever more exciting times are yet to come. The Editors ACKNOWLEDGEMENTS - Publication of this book was generously supported by Sanofi-Aventis Hellas. - Eikon creative team provided the technical assistance in preparing the manuscripts. - We thank Dr. Bernard Swynghedauw for all his scientific support.
Effective new treatments of heart disease are based on a refined understanding of cellular function and the heart's response to environmental stresses. Not surprisingly therefore, the field of experimental cardiology has experienced a phase of rapid expo- nential growth during the last decade. The acquisition of new knowledge has been so fast that textbooks of cardiology or textbooks of cardiovascular physiology are often hard-pressed to keep up with the most important conceptual advances. Witness the explosive increase in knowledge about signaling pathways of cardiac growth, transcrip- tional regulation of cardiac metabolism, hormonal signaling, and the complex responses of the heart to ischemia, reperfusion, or ischemic preconditioning. This book is meant to bridge the gap between original literature and textbook reviews. It brings together inves- tigators of various backgrounds who share their expertise in the biology of myocardial ischemia. Each chapter is a self-contained mini-review, but it will soon become apparent to the reader that there is also a common thread: Molecular and cellular cardiology has never been more exciting than now, but ever more exciting times are yet to come. The Editors ACKNOWLEDGEMENTS - Publication of this book was generously supported by Sanofi-Aventis Hellas. - Eikon creative team provided the technical assistance in preparing the manuscripts. - We thank Dr. Bernard Swynghedauw for all his scientific support.

From Fetal to Fatal.- Myocardial Ischemia.- Hormones Signaling and Myocardial Ischemia.- Ischemic Preconditioning.- Connexin 43 and Ischemic Preconditioning.- Coronary Microembolization.- Fibroblast Growth Factor-2.- Myocardial Protection — From Concepts to Clinical Practice.- A Synopsis.

Erscheint lt. Verlag 8.3.2006
Reihe/Serie Basic Science for the Cardiologist
Basic Science for the Cardiologist
Zusatzinfo VIII, 204 p.
Verlagsort New York
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Chirurgie
Medizinische Fachgebiete Innere Medizin Kardiologie / Angiologie
Schlagworte Adaptation • Development • growth • Growth factor • heart • Heart disease • Hormone • hormones • pathophysiology • Physiology • Stress
ISBN-10 0-387-28658-6 / 0387286586
ISBN-13 978-0-387-28658-7 / 9780387286587
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