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Insulin Resistance and Polycystic Ovarian Syndrome (eBook)

Pathogenesis, Evaluation, and Treatment
eBook Download: PDF
2009 | 2007
XVI, 475 Seiten
Humana Press (Verlag)
978-1-59745-310-3 (ISBN)

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Polycystic Ovarian Syndrome (PCOS) is the most common endocrinopathy in women of reproductive age. Providing a state-of-the-art analysis of the connection between insulin resistance and PCOS, this book comprehensively covers a range of topics. It provides an up-to-date and balanced overview of PCOS, with specific attention to the role of insulin resistance in its pathogenesis. It also examines diet and lifestyle factors in the aetiology and management of PCOS.


Despite dizzyingly fast-paced advances over the past two decades, even the definition of Polycystic Ovarian Syndrome (PCOS) remains in dispute. Insulin Resistance and Polycystic Ovarian Syndrome: Pathogenesis, Evaluation, and Treatment highlights the recent transition of PCOS from an infertility disorder with a diagnosis based on ovarian tissue histology to a more complex clinical entity, a metabolic disorder in which insulin resistance plays a central role.  With an expert panel of authors, each chapter provides an up-to-date and balanced overview of PCOS, paying special attention to the central role of insulin resistance in the syndrome's pathogenesis and in the management of its reproductive and metabolic abnormalities.Comprehensive and thought-provoking, Insulin Resistance and Polycystic Ovarian Syndrome: Pathogenesis, Evaluation, and Treatment is an invaluable resource for endocrinologists, gynecologists, and internists eager to learn more about this controversial and challenging disease.

1. EVALUATION FOR INSULIN RESISTANCE AND CO-MORBIDITIES RELATED TO
INSULIN RESISTANCE IN PCOS
Ricardo Azziz, MD, MPH, MBA
Dept. of Ob/Gyn, Cedars-Sinai Medical Center, and Depts. of Ob/Gyn and
Medicine, The David Geffen School of Medicine at UCLA, Los Angeles, CA,
USA

2. FAT DISTRIBUTION AND ADIPOSE PRODUCTS IN PCOS
Running title: Adipose products in PCOS
Enrico Carmina, M.D.
Department of Clinical Medicine, University of Palermo, Palermo, Italy

3. Treatment of Infertility in PCOS: Ovulation Induction
Running head: Ovulation Induction in PCOS
Authors: Deborah S. Wachs, MD
University of California, San Diego
School of Medicine
Department of Reproduction Medicine
*R. Jeffery Chang, MD
University of California, San Diego
School of Medicine
Department of Reproduction Medicine

4. IMAGING STUDIES IN POLYCYSTIC OVARY SYNDROME
Sophie JONARD, MD 1, Yann ROBERT, MD 2, Yves ARDAENS, MD 2 and Didier
DEWAILLY, MD 1
1 Department of Endocrine Gynaecology and Reproductive Medecine,
Hopital Jeanne de Flandre, Centre Hospitalier et Universitaire de
Lille, France
2 Department of Radiology, Hopital Jeanne de Flandre, Centre
Hospitalier et Universitaire de Lille, France




5. GENES RELATED TO METABOLIC ABNORMALITIES OR INSULIN RESISTANCE IN
PCOS
SHORT TITLE: Insulin resistance genes in PCOS
Héctor F. Escobar-Morreale, MD, PhD
Department of Endocrinology, Hospital Ramón y Cajal & Department of
Medicine, Universidad de Alcalá, Madrid, Spain

6. ANTI-ANDROGENS
Kür_ad Ünlühizarci, M.D. and Fahrettin Kele_timur, M.D.
Department of Endocrinology, Erciyes University Medical School,
Kayseri, Turkey

7. LIPID ABNORMALITIES IN PCOS
Abbreviated title: Lipids and PCOS
Djuro Macut, M.D., PhD.
Institute of Endocrinology, Diabetes and Diseases of Metabolism, Dr
Subotica 13, 11000 Belgrade, Serbia

8. Serine Phosphorylation,Insulin Resistance, and the Regulation OF
ANDROGEN SYNTHESIS
Running title: Serine phosphorylation, insulin resistance, and
steroidogenesis
Andrew A. Bremer M.D., Ph.D.*, Walter L. Miller, M.D.
Department of Pediatrics, University of California, San Francisco
*Supported by Pediatric Endocrinology Training Grant T32 DK07161

9. CHRONIC TREATMENT OF POLYCYSTIC OVARIAN SYNDROME:
ORAL CONTRACEPTIVE PILLS
Running Title: PCOS and OCP treatment
Shahla Nader, M.D.
Departments of Obstetrics, Gynecology & Reproductive Sciences and
Internal Medicine
The University of Texas Medical School - Houston

10. INSULIN SENSITIZING DRUGS FOR THE TREATMENT OF INFERTILITY IN
POLYCYSTIC OVARY SYNDROME
(Insulin Sensitizing Drugs in PCOS)
Cynthia S. Ryan, MDa, John E. Nestler, MDbc
aClinical Fellow, Division of Endocrinology and Metabolism, Medical
College of Virginia, Virginia Commonwealth University, Richmond,
Virginia
bWilliam G. Blackard Professor of Medicine and Chair, Division of
Endocrinology and Metabolism, Medical College of Virginia, Virginia
Commonwealth University; and cVice Chair Department of Internal
Medicine, Medical College of Virginia, Virginia Commonwealth
University, Richmond, Virginia

11. DIET AND LIFESTYLE FACTORS IN THE AETIOLOGY AND MANAGEMENT OF
POLYCYSTIC OVARY SYNDROME
R. J. NORMAN1 and L.J. MORAN2
1Research Centre for Reproductive Health and Repromed,
The Queen Elizabeth Hospital
University of Adelaide
South Australia, Australia
2CSIRO Human Nutrition,
Kintore Avenue, Adelaide 5000
South Australia, Australia

12. ADRENARCHE: THE INTERRELATIONSHIP OF ANDROGENS/ INSULIN ON THE
DEVELOPMENT OF THE METABOLIC SYNDROME/ PCOS
Running Head: Adrenarche: Metabolic Syndrome/ PCOS
Authors: Sharon E. Oberfield, M.D(1), Natasha Leibel, M.D. (1), Lauren
Antler B.A. (1), Miriam Silfen, M.D. (1), Lenore S. Levine, M.D. (1),
Mary Horlick, M.D.

Erscheint lt. Verlag 21.12.2009
Reihe/Serie Contemporary Endocrinology
Contemporary Endocrinology
Zusatzinfo XVI, 475 p.
Verlagsort Totowa
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Gynäkologie / Geburtshilfe
Medizinische Fachgebiete Innere Medizin Diabetologie
Medizinische Fachgebiete Innere Medizin Endokrinologie
Medizin / Pharmazie Pflege
Schlagworte Diabetes • Infertility • Insulin • insulin resistance • Internal Medicine • Internist
ISBN-10 1-59745-310-2 / 1597453102
ISBN-13 978-1-59745-310-3 / 9781597453103
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