Nuclear Hepatology (eBook)

A Textbook of Hepatobiliary Diseases

Gerbail T. Krishnamurthy, S. Krishnamurthy (Autoren)

eBook Download: PDF

2009 | 2nd ed. 2009
XII, 368 Seiten
Springer Berlin (Verlag)
978-3-642-00648-7 (ISBN)

Infos

Since the publication of the first edition of Nuclear Hepatology almost 10 years ago, new advances have taken place, both in our understanding of liver pathophysiology and various imaging modalities. A unique feature of imaging of physiology is that it enables quanti- cation. Since liver physiology is complex, quantification has been a challenge. Many p- lications in the past have often included quantification based on home-made software not available for others. Thus, the comparison of results from one center to another becomes difficult, if not impossible. The second edition of Nuclear Hepatology addresses these issues. Sophisticated software for liver and gallbladder function has been tested and va- dated through many of our previous publications. Now that software is FDA approved and available for others through a commercial company, it is hoped that future publications of imaging of liver and gallbladder physiology would routinely include quantification. Although the function of the hepatocyte is complex, it can be broadly divided into two main categories, substrate uptake at the basolateral border and intracellular transit prior to excretion into the canaliculi. The earliest manifestation of hepatocellular injury occurs in the form of prolongation of the intracellular transit time, which occurs long before the disruption of the basolateral border with subsequent rupture and death. The liver enzymes are released into circulation after the death of the hepatocyte.

Inhalt

Preface to the Second Edition 6
Contents 7
1 Morphology and Microstructure of the Hepatobiliary System 10
1.1 Morphology 10
1.2 Microstructure 28
References 34
2 Liver and Spleen Function 36
2.1 Liver Function 36
References 53
2.2 Spleen Function 54
References 56
3 Imaging Agents 57
3.1 Morphology and Physiology Imaging Agents 57
3.2 Radiolabeling of Red Blood Cells and Leucocytes 78
3.3 Gallium-67 Citrate 81
3.4 Somatostatin Receptor Imaging Agent 83
3.5 Fluorine18, 2-Flouro-2-deoxy- D -glucose ( 18 F-FDG) 85
4 Imaging of Liver and Spleen Morphology 92
4.1 Imaging with Radiocolloid 92
4.2 Adenoma and Focal Nodular Hyperplasia 106
4.3 Hemangioma 113
4.4 Somatostatin Receptor Scintigraphy 121
5 Imaging and Quantification of Hepatobiliary Function 131
5.1 Hepatobiliary Imaging 131
5.3 Hepatopulmonary Syndrome 166
5.4 Duodenogastric Bile Re. ux 172
5.5 Imaging and Quantification of Hepatocyte Asialoglycoprotein Receptors with Tc-99m Galactosyl Human Serum Albumin 177
6 Gallbladder, Sphincter of Oddi, Cholecystokinin, and Opioid Relation 180
6.1 Effect of Cholecystokinin on the Gallbladder and Sphincter of Oddi 180
6.2 Opioids 195
7 Intrahepatic Cholestasis 201
7.1 Imaging with Tc-99m HIDA 201
7.2 Imaging with Tc-99m Galactosyl Human Serum Albumin 211
8 Extrahepatic Cholestasis 214
8.1 Intraluminal Causes 214
8.2 Wall Thickening 227
8.3 Combined Intrahepatic and Extrahepatic Cholestasis (Sclerosing Cholangitis) 238
8.4 Extrinsic Compression 242
9 Diseases of the Gallbladder 245
9.1 Chronic Calculous Cholecystitis 248
9.2 Chronic Acalculous Cholecystitis 259
9.3 Acute Cholecystitis 274
9.4 Management of Gallbladder Disease 292
10 Biliary Dyskinesia 300
11 Pediatric Nuclear Hepatology 319
11.1 Congenital Biliary Atresia vs. Neonatal Hepatitis 319
11.2 Cystic Diseases of the Hepatobiliary System 332
12 Malignant Liver Lesions 341
12.1 Management 346
13 Liver Transplantation 347
13.1 Types of Liver Transplantation 347
13.2 Normal Functioning Liver Transplant 351
Index 363

Produkt-Details

• Erscheint lt. Verlag: 23.6.2009
• Zusatzinfo: XII, 368 p. 183 illus., 35 illus. in color.
• Verlagsort: Berlin
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Chirurgie
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Innere Medizin
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pädiatrie
• Themenwelt: Medizinische Fachgebiete ► Radiologie / Bildgebende Verfahren ► Radiologie
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
• Schlagworte: Diagnosis • hepatobiliary diseases • hepatology • Imaging • Liver • liver transplantation • nuclear hepatology • Nuclear Medicine • Pediatrics • Radiology • Transplantation
• ISBN-10: 3-642-00648-5 / 3642006485
• ISBN-13: 978-3-642-00648-7 / 9783642006487