Prostate Cancer (eBook)
XXI, 508 Seiten
Humana Press (Verlag)
978-1-59745-224-3 (ISBN)
Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, reviews new, valuable approaches to the treatment of prostate cancer in men. The latest edition contains new material on molecular imaging, new treatments for prostate cancer, molecular targets, cell signaling pathways, bioinformatics, and pathogenomics. The book details the latest innovations and advances in prostate cancer and may be used as a rapid reference text for readers.
The volume profiles the latest advances in cancer research and treatment and includes profound studies in prostate stem cells, cancer-host interactions, hedgehog signaling in development and cancer, cholesterol and cell signaling, gene therapy for advanced prostate cancer, and noninvasive strategies such as molecular imaging to visualize gene expression. This new edition also investigates expression profiling and somatic alterations in prostate cancer progression and linkage studies of prostate cancer families to identify susceptibility genes. The issues of racial differences in prostate cancer mortality, radiotherapy for the treatment of locally advanced prostate cancer, recombinant antibody candidates for treatment, taxane-based chemotherapy, lethal phenotypes, and novel and efficient translation clinical trials are also presented in great depth.
Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, provides readers with a general reference for prostate cancer from prevention to therapy and will be of value to clinicians, scientists, and administrators who strive to solve the cancer problem.
Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, reviews new, valuable approaches to the treatment of prostate cancer in men. The latest edition contains new material on molecular imaging, new treatments for prostate cancer, molecular targets, cell signaling pathways, bioinformatics, and pathogenomics. The book details the latest innovations and advances in prostate cancer and may be used as a rapid reference text for readers. The volume profiles the latest advances in cancer research and treatment and includes profound studies in prostate stem cells, cancer-host interactions, hedgehog signaling in development and cancer, cholesterol and cell signaling, gene therapy for advanced prostate cancer, and noninvasive strategies such as molecular imaging to visualize gene expression. This new edition also investigates expression profiling and somatic alterations in prostate cancer progression and linkage studies of prostate cancer families to identify susceptibility genes. The issues of racial differences in prostate cancer mortality, radiotherapy for the treatment of locally advanced prostate cancer, recombinant antibody candidates for treatment, taxane-based chemotherapy, lethal phenotypes, and novel and efficient translation clinical trials are also presented in great depth. Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, provides readers with a general reference for prostate cancer from prevention to therapy and will be of value to clinicians, scientists, and administrators who strive to solve the cancer problem.
Foreword 6
Preface 10
Contents 13
Contributors 16
I Biology and Imaging 21
Xenograft Models of Human Prostate Cancer 22
The Pathology of Human Prostatic Atrophy and Inflammation 51
Tissue Microarrays in Prostate Cancer Research 67
Prostate (Cancer) Stem Cells 81
Cancer–Host Interactions 91
Androgen Receptor Function in Prostate Cancer Progression 105
Hedgehog Signaling in Development and Cancer 124
Cholesterol, Cell Signaling, and Prostate Cancer 136
Gene Therapy for Advanced Prostate Cancer 155
Role of Transforming Growth Factor-ß in Immunotherapy of Prostate Cancer 180
Biology and Therapeutic Basis of Prostate Cancer Bone Metastasis 190
Molecular Imaging 207
Quantum Dot Nanotechnology for Prostate Cancer Research 244
II Genetics 258
Expression Profiling of Prostate Cancer Progression 259
Somatic Alterations in Prostate Cancer Progression 280
Linkage Studies of Prostate Cancer Families to Identify Susceptibility Genes 295
Somatic DNA Methylation Changes and Prostatic Carcinogenesis 310
Telomeres, Telomerase, Chromosome Stability, and Prostate Cancer 325
III Therapeutics 361
Racial Differences in Prostate Cancer Mortality 362
Radiotherapy for the Treatment of Locally Advanced Prostate Cancer 384
Recombinant Antibody Candidates for Treatment of Prostate Cancer 404
Differentiation Agents and Epigenomic Therapies 418
Taxane-Based Chemotherapy for Prostate Cancer 451
Co-Targeting Therapeutics for Hormone Refractory Prostate Cancer 469
Intercellular Targets of Prostate Cancer 480
Novel and Efficient Translational Clinical Trial Designs in Advanced Prostate Cancer 492
Index 501
| Erscheint lt. Verlag | 10.11.2007 |
|---|---|
| Reihe/Serie | Contemporary Cancer Research | Contemporary Cancer Research |
| Zusatzinfo | XXI, 508 p. |
| Verlagsort | Totowa |
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
| Medizinische Fachgebiete ► Radiologie / Bildgebende Verfahren ► Radiologie | |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Urologie | |
| Schlagworte | Cancer • Carcinogenesis • Cell • Chemotherapy • clinical trial • gene therapy • Genetics • genomics • hormones • Imaging • immunotherapy • Molecular Imaging • Mortality • Prostate Cancer • Radiaton Oncology • radiotherapy |
| ISBN-10 | 1-59745-224-6 / 1597452246 |
| ISBN-13 | 978-1-59745-224-3 / 9781597452243 |
| Haben Sie eine Frage zum Produkt? |
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