Molecular and Cell Biology of Autoantibodies and Autoimmunity. Abstracts
Springer Berlin (Verlag)
978-3-540-51436-7 (ISBN)
Clinical and Etiopathogenetic Significances of Autoantibodies to the Cellular Antigens in Systemic Connective Tissue Diseases.- Cloning of a cDNA-Fragment Coding for an Epitope Recognized by Anti-PM/Scl-Autoantibodies.- Fibrillarin from Xenopus laevis: cDNA Cloning and Expression During Development.- Nuclear Receptors as Transcriptional Enhancers.- Multiple Components of SS-A/Ro Autoantigen: cDNA Cloning of the 52 kDa Protein.- Autoantibodies to Nuclear Envelope Proteins: Characterization and Clinical Significance.- Cloned Human snRNP Proteins B and B? Differ Only in Their Carboxy-Terminal Part.- Antibodies to Ribonucleoprotein (RNP) from Autoimmune Sera Detected by Immunoblot on Tissue Extracts.- Analysis of the 60 kD Ro Protein - hY RNA Complex: An RNA Recognition Motif Within Ro Protein is Required for Binding to hY 1 RNA.- Monoclonal Autoantibodies Against Nuclear Proteins.- Alterations of the Macrophage System in Systemic Lupus Erythematosus (SLE) Developing NZB/W Mice.- Cytoskeletal Proteins: Major Antigens in Autoimmune Diseases.- Leucine Periodicity of U2 snRNP Autoantigen A? Implicated in U2 snRNP Protein: Protein Interactions.- Epitope Mapping of the Recombinant Human U1 snRNP 68 k Protein.- Molecular Characterization of the PM/SCL Antigen.- Chronic Graft-versus-Host Disease. A Model for the Study of the Autoimmune Phenomenon.- Immunogenetic Studies in Patients with Scleroderma-Associated Autoantibodies.- The TH Ribonucleoprotein Particle: Identity with RNase MRP and Association with RNase P.- Immunoregulatory Effects of Borrelia Burgdorferi Antigens in Patients with Chronic Lyme Disease.- Molecular Mimicry: A Common Epitope of the (U 1) snRNP Associated p68 Autoantigen and a Protein of a Human Pathogenic Virus.- Human Autoantibodies to SynaptonemalComplex.- Immunolocalization and Number of Transcriptionally Active rRNA Genes in Vertebrate Cells.- Mapping of Autoimmune Reactive Sites on snRNP Proteins.- Clinical Significances of Rare Autoantibodies to Small Nuclear and Cytoplasmic Ribonucleoproteins.- Molecular Cloning and Expression of cDNAs Encoding snRNP Polypeptide Autoantigens.- U 1-68 Kd Protein-Positive Mixed Connective Tissue Disease is Associated with HLA-DR4 and Appears Genetically Distinct from Systemic Lupus Erythematosus.- A Novel Trait of Naturally-Occurring Anti-DNA Antibodies: Dissociation from Immune Complexes in Neutral 0.3-0.5 M NaC1.- Immunoblotting Analysis in Antigenic Components of Circulating Immune Complexes of Rheumatoid Arthritis and Systemic: Lupus Erythematosus Patients.- The Human La Autoantigen Contains an RNA Binding Domain and an ATP Binding Domain.- Autoantibodies to "HSP 70 Class" Proteins in Sera of Systemic Lupus Erythematosus (SLE) Patients and Healthy Subjects. A Spontaneous Expression of HSP 70 Autoantibodies.- Cross-Reactive Rheumatoid Factor in Rheumatoid Arthritis with Extra-Articular Disease.- Profiles of Anti-Nuclear Antibodies in Scleroderma Spectrum Disorders.- Desmin Antibodies in Acute Myopericarditis.- Ankylosing Spondylitis (AS) and Rheumatoid Arthritis (RA): Improved Diagnosis and Attempts Towards the Molecular Analysis of Etiology and Pathogenesis of These Systemic Rheumatic Diseases.- Characterization of the snRNP Protein N: Description of a Potential Sm Epitope.- Antigenic Structure of U snRNPs and Experimental Induction of Anti-U snRNP Autoantibodies in Mice.- The U 1 RNA Binding Site of the U 1 snRNP-Associated A Protein Overlaps an Anti-U1 RNA Antibody Binding Site.- Anti-Ribosomal P Protein Antigens and Antibodies.- Molecular Identification of theM2 Antigens of Primary Biliary Cirrhosis.- Molecular Biological Identification of Autoantigens in Autoimmune Hepatitis - Relevance for Pathogenesis, Diagnosis, and Treatment.- Aminoacyl-tRNA Synthetases: an Overview.- A New Autoantibody Specific for the Limited Systemic Sclerosis (lSSc) Found Through Molecular Biology.- Determination of an Epitope of the Diffuse Scleroderma Marker Antigen Topoisomerase I. Sequence Similarity with Retroviral p 30gag Protein Suggests a Possible Cause for Autoimmunity in Scleroderma.- The Spectrum of Antinuclear Antibodies (ANA) and Clinical Findings in Children with Anti-U 1-RNP Antibodies.- Molecular Cloning of the Human Autoantigen KU (p 70/p 80), a DNA-Terminal-Binding Protein Complex.- Autoantibodies to a Histone Cross-Reactive DNA-Binding Protein of Mr 110000 in Systemic Lupus Erythematosus and Other Diseases and in Autoimmune Mice.- cDNA Cloning and Expression of U1snRNP C Protein.- Further Characterization of the Anti-Wa Antibody to a tRNA-Related Protein in Progressive Systemic Sclerosis.- Characteristics and Interrelation of Autoantibodies in Scleroderma Sera.- Characterization of an Autoantigen in Graves' Hyperthyroidism.- Clinical Significance of Anti-Ubiquitin Antibodies in Systemic Lupus Erythematosus.- The Natural History of PCNA/Cyclin.- Identification of Several Independent Autoreactive Epitopes of the Human 68 kDa (U 1) snRNP-Autoantigen.- Current Ideas on Tolerance Mechanisms and Autoimmunity.- Molecular Cloning of a cDNA for the B-Polypeptide of the U snRNPs.- The Induction of Anti-DNA Antibodies in Normal Mice by Immunization with Bacterial DNA.- The Binding of Anti-La Antibodies to Fusion Proteins Containing Various La Epitopes.- Isolation and Sequencing of Human Lamin ? cDNA: Mammalian Lamins A, B and C ContainLeucine Heptad Repeats.- Detection of Autoantibodies Using Recombinant Antigens.- A Common RNA Recognition Motif Identified Within a Defined U 1 RNA-Binding Domain of the 70K U1 snRNP Autoantigen.- Characterization of Nucleolar 7-2 RNP Recognized by Sera from Patients with Autoimmune Diseases.- Structure and Antigenicity of the p70 (Ku) Autoantigen.- Synthetic Peptides as Probes for Autoantibodies.- cDNA Sequencing and Expression of B/B?-Proteins of RNP Autoantigens in E. coli.- Compartmentalization of Nuclear Antigens Detected by Autoantibodies.- Anti-A. R.: A New Autoantibody/ies in Autoimmune Chronic Active Hepatitis (CAH) that Precipitates a 4.5 S RNA.- Immunological Crossreactivity Between RNA Polymerase I and the Glycine Rich Repeats of Epstein-Barr Virus Nuclear Antigen.- Drug Induced Anti-Histone Antibodies Reflect Nucleosomal Substructures.- Epitope Mapping of the Ro-RNP Autoantigen Using Recombinant Polypeptides.- Idiotype Network and Anti-DNA Antibody Production.- In Vitro Binding of A and B? snRNP Proteins to U1 and U2 snRNAs.- Expression of the 70 kD RNP Autoantigen in E. coli and Its Use in ELISA-Screening of Patients Sera.- The Autoantibody Expression in Cultured Cell Lines of Human Keratinocytes Transformed by Virus and by Ultraviolet Light in SLE and Other Autoimmune Diseases.- The B Cell Activation in Autoimmunity.- Rheumatoid Factor Idiotypes in Lymphoproliferative Disorders in Patients with Sjörgren's Syndrome.- Snurps and Scyrps - Insights into the Biology of RNA Processing.- Genetic Restriction of Autoantibody Production in Patients with Systemic Lupus Erythematosus.- Localization of an Immunopathologically Important Epitope in the Bovine Retinal S-Antigen by the Pepscan Method.- Anti-Peptide Antibodies to Three CDR Sequences of HumanMonoclonal Anti-DNA Autoantibodies.- Immunological Characterization of IgM Class Autoantibodies Against Sm-Antigenic B?/B and D Polypeptides of U Small Nuclear Ribonucleoproteins (snRNPs).- Enzyme-Linked Immunosorbent Assay Using Isolated (U) Small Nuclear Ribonucleoprotein Polypeptides as Antigens.- Analysis of U1 Ribonucleoprotein (RNP) 68K Polypeptide (p 68K) Epitopes by Enzyme-Linked Immunosorbent Assay (ELISA) with Fusion Proteins (FPs).- Contributions of Molecular and Cell Biology to Understanding of the B-Cell Response in Systemic Autoimmunity.- Immunospecificity and Clinical Association of Autoantibodies in Sera Precipitating U1 and U2 Small Nuclear RNAs.- Anti-JO-1 Antibodies are Directed at an Evolutionarily-Conserved, Conformational Site on Human Histidyl-tRNA Synthetase.- Molecular Considerations of Primary Biliary Cirrhosis: Definition of Dihydrolipoamide Acetyltransferase and Identification of Immunoreactive Sites.- Association of Seropositive Rheumatoid Arthritis (RA) with the Third Hypervariable Region (HVR3) of the HLA-DR ?1-Chain: Functional Implications for Antigen-Specific and Allogeneic T Cell Recognition.- The snRNP E Protein: Structure and Expression of a Human Autoimmune Antigen.- Autoantibodies to Nonhistone Chromosomal Proteins HMG-1 and HMG-2 in Subsets of Juvenile Chronic Arthritis (JCA).- A Human T Cell Clone Recognizing Small Nuclear Ribonucleoproteins (UsnRNP).- Epitope Progression in Autoantibody Production Suggested by Epitope Mappings of SS-B/La and U2snRNP B? Protein.- Association of Autoantigenic Epitope and Catalytic Site on Poly (ADP-Ribose) Polymerase.- Rheumatoid Arthritis is Associated with the Presence of Anti-Nuclear Antibodies to a 33kD Protein (RA 33) and Related Antigens.- Molecular Cloning and Identification ofRetroviral Nucleic Acids Associated with Systemic Lupus Erythematosus.- Molecular Features of an RNA Recognition Motif Family of Proteins.- Detection of HIV-Homologous DNA and RNA in Systemic Lupus Erythematosus.- Heterogeneity of the Ro(SSA) Antigen and the Autoanti-Ro(SSA) Response: Evidence for 4 Antigenically Distinct Forms.- Molecular Cloning of Ki Antigen C DNA and Enzyme-Linked-Immunosorbent-Assay for Anti-Ki Using Recombinant Ki.- Antibodies to Nuclear Lamin C in Chronic Hepatitis Delta Virus Infection.
| Erscheint lt. Verlag | 25.7.1989 |
|---|---|
| Reihe/Serie | Sitzungsber.Heidelberg 89 | Sitzungsberichte der Heidelberger Akademie der Wissenschaften |
| Zusatzinfo | XV, 118 p. 8 illus. in color. |
| Verlagsort | Berlin |
| Sprache | englisch |
| Maße | 170 x 244 mm |
| Gewicht | 290 g |
| Themenwelt | Sachbuch/Ratgeber ► Gesundheit / Leben / Psychologie ► Lebenshilfe / Lebensführung |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Dermatologie | |
| Studium ► Querschnittsbereiche ► Infektiologie / Immunologie | |
| Schlagworte | autoantibodies • Autoantigenes • autoimmunity • Dermato/Polymyositis • Lupus • Precursor mRNA • Ribonucleoproteins • scleroderma • Sjogren's Syndrome • Small Nuclear • splicing |
| ISBN-10 | 3-540-51436-8 / 3540514368 |
| ISBN-13 | 978-3-540-51436-7 / 9783540514367 |
| Zustand | Neuware |
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