Principles of Free Radical Biomedicine
Volume 2
2012
Nova Science Publishers Inc (Verlag)
978-1-61209-774-9 (ISBN)
Nova Science Publishers Inc (Verlag)
978-1-61209-774-9 (ISBN)
Discusses the biochemistry and cellular/molecular biology of free radicals, transition metals, oxidants and antioxidants, and the role of oxidative stress in human health and disease.
Recent years have witnessed an avalanche of new knowledge implicating free radicals in virtually every aspect of biology and medicine. It is now axiomatic that the regulated accumulation of reactive oxygen species (ROS) contributes to organismal health and well-being and that ROS serve as signaling molecules involved in cell growth, differentiation, gene regulation, replicative senescence and apoptosis. This book is an interdisciplinary text broken up into three consecutive volumes on the biochemistry and cellular/molecular biology of free radicals, transition metals, oxidants and antioxidants, and the role of oxidative stress in human health and disease.
Recent years have witnessed an avalanche of new knowledge implicating free radicals in virtually every aspect of biology and medicine. It is now axiomatic that the regulated accumulation of reactive oxygen species (ROS) contributes to organismal health and well-being and that ROS serve as signaling molecules involved in cell growth, differentiation, gene regulation, replicative senescence and apoptosis. This book is an interdisciplinary text broken up into three consecutive volumes on the biochemistry and cellular/molecular biology of free radicals, transition metals, oxidants and antioxidants, and the role of oxidative stress in human health and disease.
Introduction; Non-enzymatic antioxidants; Glutathione; Vitamin C; Vitamin E; Nutritional antioxidants; Antioxidant enzymes; Superoxide dismutases; SOD mimics; Catalases; Glutathione peroxidases; Thioredoxins & glutaredoxins; Peroxiredoxins; Role & regulation of heme oxygenase in oxidative stress; NF-kB transcription factor: Mechanism of redox regulation; The Nrf2 (NFE2L2) transcription factor pathway; Redox-modulated AP-1 signaling; Subcellular Compartmentalization; Oxidative stress in mitochondria; Oxidative stress & lysosomes; Oxidative stress & peroxisomes; Oxidative stress & the endoplasmic reticulum; Metabolism & Physiology; Iron metabolism; Copper metabolism; Inflammation; Mechanisms of oxygen sensing & hypoxia.
Verlagsort | New York |
---|---|
Sprache | englisch |
Maße | 260 x 180 mm |
Gewicht | 1330 g |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Biomedizin |
Naturwissenschaften ► Biologie ► Biochemie | |
Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
ISBN-10 | 1-61209-774-X / 161209774X |
ISBN-13 | 978-1-61209-774-9 / 9781612097749 |
Zustand | Neuware |
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