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Principles of Free Radical Biomedicine - Kostas Pantopoulos, Hyman Schipper

Principles of Free Radical Biomedicine

Volume 2
Buch | Hardcover
2012
Nova Science Publishers Inc (Verlag)
978-1-61209-774-9 (ISBN)
CHF 469,95 inkl. MwSt
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Discusses the biochemistry and cellular/molecular biology of free radicals, transition metals, oxidants and antioxidants, and the role of oxidative stress in human health and disease.
Recent years have witnessed an avalanche of new knowledge implicating free radicals in virtually every aspect of biology and medicine. It is now axiomatic that the regulated accumulation of reactive oxygen species (ROS) contributes to organismal health and well-being and that ROS serve as signaling molecules involved in cell growth, differentiation, gene regulation, replicative senescence and apoptosis. This book is an interdisciplinary text broken up into three consecutive volumes on the biochemistry and cellular/molecular biology of free radicals, transition metals, oxidants and antioxidants, and the role of oxidative stress in human health and disease.

Introduction; Non-enzymatic antioxidants; Glutathione; Vitamin C; Vitamin E; Nutritional antioxidants; Antioxidant enzymes; Superoxide dismutases; SOD mimics; Catalases; Glutathione peroxidases; Thioredoxins & glutaredoxins; Peroxiredoxins; Role & regulation of heme oxygenase in oxidative stress; NF-kB transcription factor: Mechanism of redox regulation; The Nrf2 (NFE2L2) transcription factor pathway; Redox-modulated AP-1 signaling; Subcellular Compartmentalization; Oxidative stress in mitochondria; Oxidative stress & lysosomes; Oxidative stress & peroxisomes; Oxidative stress & the endoplasmic reticulum; Metabolism & Physiology; Iron metabolism; Copper metabolism; Inflammation; Mechanisms of oxygen sensing & hypoxia.

Verlagsort New York
Sprache englisch
Maße 260 x 180 mm
Gewicht 1330 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Biomedizin
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Genetik / Molekularbiologie
ISBN-10 1-61209-774-X / 161209774X
ISBN-13 978-1-61209-774-9 / 9781612097749
Zustand Neuware
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