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Modeling Fragile X Syndrome

Robert B. Denman (Herausgeber)

Buch | Hardcover

XII, 392 Seiten

2011 | 2012
Springer Berlin (Verlag)
978-3-642-21648-0 (ISBN)

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Introduction.-Probing Astrocyte Function in Fragile X Syndrome.- Neural Stem Cells.- Fragile X Mental Retardation Protein (FMRP) and the Spinal Sensory System.- The Role of the Postsynaptic Density in the Pathology of the Fragile X Syndrome.- Behavior in a Drosophila model of Fragile X.- Molecular and Genetic Analysis of the Drosophila Model of Fragile X Syndrome.- Fragile X Mental Retardation Protein and Stem Cells.- Manipulating the Fragile X Mental Retardation Proteins in the Frog.- Exploring the Zebra finch Taeniopygia gutta as a Novel Animal Model for the Speech-language Deficit of Fragile X Syndrome.- Neuroendocrine Alterations in the Fragile X Mouse.- Taking STEPs forward to understanding Fragile X Syndrome.- Fmr-1 as an Offspring Genetic and a Maternal Environmental Factor in Neurodevelopmental Disease.- Mouse Models of the Fragile X Premutation and the Fragile X Associated Tremor/Ataxia Syndrome.- Clinical Aspects of the Fragile X Syndrome.- Fragile X Syndrome: A Psychiatric Perspective.- Fragile X Syndrome and Targeted Treatment Trials.- The Fragile X-associate Tremor Ataxia Syndrome.- Vignettes: Models in Absentia.

Erscheint lt. Verlag	20.10.2011
Reihe/Serie	Results and Problems in Cell Differentiation
Zusatzinfo	XII, 392 p.
Verlagsort	Berlin
Sprache	englisch
Maße	155 x 235 mm
Gewicht	741 g
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
	Naturwissenschaften ► Biologie ► Zellbiologie
	Naturwissenschaften ► Biologie ► Zoologie
Schlagworte	epigenetics • FMR1 • FMR1 Gene • Fragile X Syndrome • FXS • gene therapy • Genetic disorder • Inherited disease • Stem Cells
ISBN-10	3-642-21648-X / 364221648X
ISBN-13	978-3-642-21648-0 / 9783642216480
Zustand	Neuware