Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism
Lippincott Williams and Wilkins (Verlag)
978-0-7817-2038-0 (ISBN)
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Part 1 Anatomy and biology of bone matrix and cellular elements: anatomy and ultrastructure of bone; bone morphogenesis and embryologic development; bone formation - osteoblast lineage cells, growth factors, matrix proteins and the mineralization process; bone remodelling; biomechanics of bone. Part 2 Skeletal physiology: childhood and adolescence; pregnancy and lactation; menopause; the aging skeleton. Part 3 Mineral homeostasis: the intestinal absorption of calcium, magnesium and phosphate; calcium, magnesium and phosphorus - renal handling and urinary excretion; mineral balance and homeostasis; parathyroid hormone; parathyroid hormone-related protein; vitamin D - photobiology, metabolism, mechanism of action and clinical applications; calcitonin; gonadal steroids and receptors. Part 4 Clinical evaluation of bone and mineral disorders: history and physical examination; blood calcium, phosphorus and magnesium; assay methods - parathyroid hormone, parathyroid hormone-related protein and calcitonin; vitamin D metabolites; biochemical markers of bone turnover; radiologic evaluation of bone mineral in children; scintigraphy in metabolic bone disease; clinical application of bone densitometry; radiology of osteoporosis; bone biopsy and histomorphometry in clinical practice; molecular diagnosis of bone and mineral disorders. Part 5 Disorders of serum minerals: hypercalcaemia - pathogenesis, clinical manifestations, differential diagnosis and management; primary hyperparathyroidism; familial hyperparathyroid syndromes; familial hypocalciuric hypercalcaemia; tertiary hyperparathyroidism and refractory secondary hyperparathyroidism; humoral hypercalcaemia of malignancy; hypercalcaemia in haematologic malignancies and in solid tumors associated with extensive localized bone destruction; hypercalcaemia due to granuloma-forming disorders; miscellaneous causes of hypercalcaemia; hypercalcaemic syndromes in infants and children; hypocalcaemia - pathogenesis, differential diagnosis and management; hypoparathyroidism; parathyroid hormone resistance syndromes; neonatal hypocalcaemia; miscellaneous causes of hypocalcaemia; magnesium depletion and hypermagnesemia; hyperphosphatemia and hypophosphatemia. Part 6 Metabolic bone diseases: epidemiology of osteoporosis; pathogenesis of postmenopausal osteoporosis; physical activity and regulation of bone mass; prevention of osteoporosis; nutrition and osteoporosis; evaluation of postmenopausal osteoporosis; pharmacology of agents to treat osteoporosis; pharmacologic treatment of postmenopausal osteoporosis; osteoporosis in men; glucocorticoid-induced osteoporosis; transplantation osteoporosis; juvenile osteoporosis; secondary causes of osteoporosis - thyrotoxicosis and lack of weight bearing; orthopaedic complications of osteoporosis; osteoporosis and rheumatic diseases; nutritional rickets and osteomalacia; metabolic bone disease of total parental nutrition; vitamin D-dependent rickets; hypophosphatemic vitamin D-resi
| Erscheint lt. Verlag | 1.9.1999 |
|---|---|
| Zusatzinfo | 256 illustrations, 80 tables |
| Verlagsort | Philadelphia |
| Sprache | englisch |
| Maße | 279 x 216 mm |
| Gewicht | 1200 g |
| Themenwelt | Medizinische Fachgebiete ► Chirurgie ► Unfallchirurgie / Orthopädie |
| Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie | |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie | |
| ISBN-10 | 0-7817-2038-9 / 0781720389 |
| ISBN-13 | 978-0-7817-2038-0 / 9780781720380 |
| Zustand | Neuware |
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