Principles of Free Radical Biomedicine
Volume 1
Seiten
2012
Nova Science Publishers Inc (Verlag)
978-1-61209-773-2 (ISBN)
Nova Science Publishers Inc (Verlag)
978-1-61209-773-2 (ISBN)
There is an avalanche of knowledge implicating free radicals in various aspects of biology and medicine. This book focuses on the biochemistry and cellular/molecular biology of free radicals, transition metals, oxidants and antioxidants, and the role of oxidative stress in human health and disease.
Recent years have witnessed an avalanche of new knowledge implicating free radicals in virtually every aspect of biology and medicine. It is now axiomatic that the regulated accumulation of reactive oxygen species (ROS) contributes to organismal health and well-being and that ROS serve as signalling molecules involved in cell growth, differentiation, gene regulation, replicative senescence and apoptosis. This book is an interdisciplinary text broken up into three consecutive volumes on the biochemistry and cellular/molecular biology of free radicals, transition metals, oxidants and antioxidants, and the role of oxidative stress in human health and disease.
Recent years have witnessed an avalanche of new knowledge implicating free radicals in virtually every aspect of biology and medicine. It is now axiomatic that the regulated accumulation of reactive oxygen species (ROS) contributes to organismal health and well-being and that ROS serve as signalling molecules involved in cell growth, differentiation, gene regulation, replicative senescence and apoptosis. This book is an interdisciplinary text broken up into three consecutive volumes on the biochemistry and cellular/molecular biology of free radicals, transition metals, oxidants and antioxidants, and the role of oxidative stress in human health and disease.
Introduction; The evolution of oxidative stress; Oxygen radicals & related species; Nitric oxide & derived oxidants; Sulfur-centered radicals; Redox active metals: iron & copper; Protein oxidation; Lipid peroxidation; Lipid nitration; DNA oxidation; Methods of investigation of selected radical oxygen/nitrogen species in cell-free & cellular systems; Enzymatic generation of hypoxia & steady-state H2O2; Chemiluminescence detection of H2O2; Index.
| Verlagsort | New York |
|---|---|
| Sprache | englisch |
| Maße | 260 x 180 mm |
| Gewicht | 780 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Biomedizin |
| Naturwissenschaften ► Biologie ► Biochemie | |
| ISBN-10 | 1-61209-773-1 / 1612097731 |
| ISBN-13 | 978-1-61209-773-2 / 9781612097732 |
| Zustand | Neuware |
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