Regulation of Tissue Oxygenation

Roland Pittman (Autor)

Buch | Softcover

100 Seiten

2010
Morgan & Claypool Publishers (Verlag)
978-1-61504-177-0 (ISBN)

Infos

This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO in their vicinity falls to a critical level of about 1 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO. In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Inhalt

Introduction
The Circulatory System and Oxygen Transport
The Respiratory System and Oxygen Transport
Oxygen Transport
Chemical Regulation of Respiration
Tissue Gas Transport
Oxygen Transport in Normal and Pathological Situations: Defects and Compensations
Matching Oxygen Supply to Oxygen Demand
Exercise and Hemorrhage
Measurement of Oxygen
Summary
References
Biography

Produkt-Details

• Erscheint lt. Verlag: 15.2.2011
• Reihe/Serie: Colloquium Series on Integrated Systems Physiology
• Verlagsort: San Rafael
• Sprache: englisch
• Maße: 187 x 235 mm
• Themenwelt: Medizinische Fachgebiete ► Innere Medizin ► Pneumologie
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie
• ISBN-10: 1-61504-177-X / 161504177X
• ISBN-13: 978-1-61504-177-0 / 9781615041770
• Zustand: Neuware