Foundations of Systems Biology

Using Cell Illustrator and Pathway Databases

Masao Nagasaki, Ayumu Saito, Atsushi Doi, Hiroshi Matsuno, Satoru Miyano (Autoren)

Buch | Softcover

155 Seiten

2017 | Softcover reprint of the original 1st ed. 2009
Springer London Ltd (Verlag)
978-1-4471-6872-0 (ISBN)

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Today, as hundreds of genomes have been sequenced and thousands of proteins and more than ten thousand metabolites have been identi?ed, navigating safely through this wealth of information without getting completely lost has become crucial for research in, and teaching of, molecular biology. Consequently, a considerable number of tools have been developed and put on the market in the last two decades that describe the multitude of potential/putative interactions between genes, proteins, metabolites, and other biologically relevant compounds in terms of metabolic, genetic, signaling, and other networks, their aim being to support all sorts of explorations through bio-data bases currently called Systems Biology. As a result, navigating safely through this wealth of information-processing tools has become equally crucial for successful work in molecular biology. To help perform such navigation tasks successfully, this book starts by providing an extremely useful overview of existing tools for ?nding (or designing) and inv- tigating metabolic, genetic, signaling, and other network databases, addressing also user-relevant practical questions like • Is the database viewable through a web browser? • Is there a licensing fee? • What is the data type (metabolic, gene regulatory, signaling, etc. )? • Is the database developed/maintained by a curator or a computer? • Is there any software for editing pathways? • Is it possible to simulate the pathway? It then goes on to introduce a speci?c such tool, that is, the fabulous “Cell - lustrator 3. 0” tool developed by the authors.

Pathway Databases.- Pathway Simulation Software.- Starting Cell Illustrator.- Pathway Modeling and Simulation.- Computational Platform for Systems Biology.

Erscheinungsdatum	23.03.2017
Reihe/Serie	Computational Biology ; 13
Zusatzinfo	XII, 155 p.
Verlagsort	England
Sprache	englisch
Original-Titel	(Japanese): Shisutemu seibutugaku ga wakaru! Seruirasutore-ta wo tsukatte miyou
Maße	155 x 235 mm
Themenwelt	Informatik ► Grafik / Design ► Digitale Bildverarbeitung
	Mathematik / Informatik ► Informatik ► Theorie / Studium
	Naturwissenschaften ► Biologie ► Zellbiologie
Schlagworte	Biology • Databases • differential equation • Genome • Information Processing • learning • Molecular Biology • Pathway Databases • Pathway Modeling • Simulation • Simulation Software • systems biology
ISBN-10	1-4471-6872-0 / 1447168720
ISBN-13	978-1-4471-6872-0 / 9781447168720
Zustand	Neuware