Microarrays

Principles, Applications & Technologies

Buch | Softcover

329 Seiten

2014
Nova Science Publishers Inc (Verlag)
978-1-62948-669-7 (ISBN)

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The sequencing of the human genome was a pivotal event in science that opened the door to exploring the structure and function of genes and their regulation. The activation or suppression of transcribed genes is critical to the orchestration of everyday biological processes at the cellular, tissue, and physiological levels. The rapid advance of science and technology has yielded the development of the microarray technique, which has propelled a much deeper understanding of the genome. By combining these technological advances in microarrays with statistical and bioinformatics software, investigators are now able to perform scientific investigations geared towards answering unique biological problems that encompass many fields of research from genetics and evolution to molecular medicine, health, and disease. This book provides an overview of the use and application of microarrays throughout the life sciences to address diverse complex biological questions. In this collection, authors present information on using microarrays to unlock molecular mechanisms and gene expression patterns associated with research areas ranging from biodefense, pathological changes, and monitoring antimicrobial resistance genes to diagnostics, marine biodiversity, and dermal toxicology.

Preface; Microarray Technology for Category (R)A - Bioterrorism Agent Research: Current Status & Perspectives; Similarity Threshold Selection Tools for Gene Co-Expression Networks; Mining Gene Expression Microarrays for Long Non-Coding RNAs; An In Situ Electroporation & Flow Device for Mechanotransduction Studies; A New Application for Microarrays: Analysis of Global MicroRNA Expression Profiles in the Extracellular Microvesicles of Human Macrophage-Like Cells; Identification of Reference Genes by Meta-Microarray Analyses; Invertebrate DNA Chip: Opportunities & Challenges in the Development & Application of Microarrays for Marine Biodiversity Studies; Using Microarrays to Decipher the Virus-Host Interactions in HCV Infected Patients: Implications for Viral Resistance, Drug Development & Personalized Medicine; Microarray Diagnostics for Orthopoxviruses, Filoviruses, Arenaviruses & Type A Influenza Virus; Using DNA Microarray Technology to Monitor the Distribution of Antimicrobial Resistance Genes in Escherichia Coli Isolated from Animal Colibacillosis Outbreaks; Phenotypic Anchoring of Liver Injury in Rats by Gene Expression Profiling; Application of Microarray Technology in Toxicology; Microarray Analysis of Gene Transcription Profiles in Chronic Rhinosinusitis; Transcriptomic Analysis of Oligomeric Amyloid-|A Treated Primary Cortical Neurons Reveals Dysregulation of Genes Involved in the Biosynthesis of Steroids & Cholesterol; Application of Microarrays to Cutaneous Chemical Exposures; Index.

Erscheint lt. Verlag	1.3.2014
Verlagsort	New York
Sprache	englisch
Maße	180 x 260 mm
Gewicht	788 g
Themenwelt	Informatik ► Weitere Themen ► Bioinformatik
Themenwelt	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
ISBN-10	1-62948-669-8 / 1629486698
ISBN-13	978-1-62948-669-7 / 9781629486697
Zustand	Neuware