Chemical Factors in Neural Growth, Degeneration and Repair (eBook)

C. Bell (Herausgeber)

eBook Download: PDF

1996 | 1. Auflage
536 Seiten
Elsevier Science (Verlag)
978-0-08-052903-5 (ISBN)

Infos

This volume provides an up-to-date survey of current thinking concerning the actions of chemical factors in the regulation of neuronal behaviour under normal and pathological conditions. The book is divided into four sections, dealing with chemical factors involved with the formation of axon pathways, factors involved with neuronal survival and specialization during normal development, factors involved in normal maintenance and repair of adult neurons and, finally, factors that have been implicated as mediators of degenerative changes in neurological and neuropsychiatric disorders.

Inhalt

Cover 1
Contents 14
List of contributors 6
Preface 8
Section I: Factors Implicated in Neural Pathway Formation 16
Chapter 1. Axon guidance factors in invertebrate development 18
Chapter 2. Adhesion molecules in neural crest development 60
Chapter 3. Laminin in neural development 82
Section II: Factors Implicated in Neuron Survival and Specialization 102
Chapter 4. Mechanisms of developmental cell death 104
Chapter 5. Regulation of the early development of the nervous system by growth factors 138
Chapter 6. Retrograde factors in peripheral nerves 164
Chapter 7. The regulation of nerve growth factor synthesis and delivery to peripheral neurons 186
Chapter 8. Brain-derived neurotrophic factor 218
Chapter 9. Neurotrophin-3 and neurotrophin-4/5 234
Chapter 10. Centrally-active differentiation factors in the nervous system 266
Chapter 11. Leukemia inhibitory factor and phenotypic specialization 280
Chapter 12. Ciliary neurotrophic factor 308
Section III: Factors Implicated in Neuronal Support and Repair 324
Chapter 13. Melanocortins as factors in somatic neuromuscular growth and regrowth 326
Chapter 14. Functions of fibroblast growth factors (FGFs) in the nervous system 354
Chapter 15. Astroglial neurotrophic and neurite-promoting factors 392
Chapter 16. Roles of insulin-like growth factors in peripheral nerve regeneration and motor neuron survival 414
Section IV: Factors Implicated in Neuronal Damage 438
Chapter 17. Oxidative stress: free radical production in neural degeneration 440
Chapter 18. Excitotoxic neuronal damage and neuropsychiatric disorders 526
Subject Index 546

Produkt-Details

• Erscheint lt. Verlag: 17.12.1996
• Sprache: englisch
• Themenwelt: Geisteswissenschaften ► Psychologie ► Entwicklungspsychologie
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
• Themenwelt: Naturwissenschaften ► Biologie ► Humanbiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Zoologie
• ISBN-10: 0-08-052903-8 / 0080529038
• ISBN-13: 978-0-08-052903-5 / 9780080529035